Premium methylated B6, folate and B12. One tablet a day.
NeuroThrive™ MTHFR & Homocysteine Support delivers three key B vitamins already in their active, methylated form: methylfolate (5-MTHF), methylcobalamin and P-5-P. No folic acid. No cyanocobalamin. The forms your body can use directly, with no conversion step.
At a glance
Methylfolate (5-MTHF) · Methylcobalamin · P-5-P
1 tablet daily with food · 30 tablets, one month
Vegan · Non-GMO · Gluten free · GMP certified · Made in the EU
Try it without the risk. If it doesn't suit you, email james@neurothrive.ie within 30 days for a full refund. No questions asked, and you don't need to send the tub back.
What's Inside
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Folate (B9): Methylfolate (5-MTHF), 400mcg. The active form, so no conversion step is needed.
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Vitamin B12: Methylcobalamin, 1000mcg. The active form of B12.
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Vitamin B6: P-5-P (Pyridoxal-5-Phosphate), 1.5mg. The active coenzyme form of B6.
What they contribute to
- Contributes to normal homocysteine metabolism
- Contributes to normal energy-yielding metabolism and the reduction of tiredness and fatigue
- Contributes to normal functioning of the nervous system
- Contributes to normal psychological function
Authorised EU health claims for vitamins B6, B9 and B12.
How To Take It
One tablet daily with food. Morning is best, as some people find an evening dose doesn't suit them.
If you're new to methylated B vitamins, you could start with one tablet every second day for the first week, then move to daily.
Give it time. Consistent daily use over two to three months is a fairer test than a fortnight.
Planning to take it for the full two to three months?
It's the same formula either way. A longer supply costs less per day, and the 90 Tablet Bottle gives you three months in one bottle.
See the 90 Tablet Bottle →
Why Methylated Forms
Standard supplements use folic acid, cyanocobalamin and pyridoxine: forms that need converting before your body can use them. NeuroThrive™ uses 5-MTHF, methylcobalamin and P-5-P, the already-active forms.
Read our full guide: Methylated vs Standard B Vitamins →
Who It's For
- Anyone who prefers active, methylated forms of B vitamins
- People looking for a folate supplement that doesn't rely on folic acid
- People who have had MTHFR genetic testing and want to learn more
New to MTHFR? Read our complete guide →
Common Questions
How is this different from a standard B-complex?
Standard B-complexes use folic acid, cyanocobalamin and pyridoxine. NeuroThrive™ uses the already-active forms, so no conversion step is required.
Can I take this if I don't know my MTHFR status?
Yes. Methylated B vitamins are suitable for the general population, whether or not you've been tested.
When will it arrive?
Orders are dispatched from Ireland. Ireland and UK typically arrive within 2–4 working days, the rest of the EU within 5–7.
Can I take this alongside medication?
Please consult your GP or pharmacist if you take prescription medication, particularly methotrexate or anticonvulsants.
Is it suitable during pregnancy?
Folate matters during pregnancy, but dosage should be discussed with your GP or midwife. Please speak to them before starting any supplement while pregnant or breastfeeding.
What if it doesn't suit me?
30-day money-back guarantee. Contact james@neurothrive.ie within 30 days for a full refund, no questions asked.
Why We Built It
NeuroThrive™ was founded by James O'Neill after years of being told his daughter's results were normal. They weren't. A single blood test finally found a severe MTHFR variant that standard testing never thought to look for — and that answer changed everything. It's why this brand exists, so the next family doesn't have to search as long.
Read the full story →
Vegan · Non-GMO · Gluten Free · GMP Certified · FSAI Registered · Made in EU · Irish-Owned
Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Consult your GP before beginning any new supplement programme, particularly if you are pregnant, breastfeeding, or taking prescription medication.
