NeuroThrive™ MTHFR & Homocysteine Support ★★★★★

Struggling with fatigue, brain fog, anxiety, or low mood that nothing seems to shift? Your B vitamins may be the problem, not the solution.

Standard B vitamins need to be converted by the MTHFR enzyme before your body can use them. If you carry an MTHFR gene variant — which affects up to 1 in 2 people — that conversion is impaired. You could be taking B vitamins every day and still be short of the forms that actually matter.

NeuroThrive™ MTHFR & Homocysteine Support delivers all three key B vitamins already in their active, methylated form. No conversion required — the nutrients your body can use from the moment you take them.

What's Inside

• Folate (B9) — Methylfolate (5-MTHF), 400mcg. The active form that bypasses the MTHFR conversion step entirely.
• Vitamin B12 — Methylcobalamin, 1000mcg. The neurologically active form, supporting nerve function and homocysteine metabolism.
• Vitamin B6 — P-5-P (Pyridoxal-5-Phosphate), 1.5mg. The active coenzyme form, supporting homocysteine clearance.

1 tablet daily with food · 30 tablets (1-month supply)

Key Benefits

• Contributes to normal homocysteine metabolism
• Contributes to normal energy-yielding metabolism and the reduction of tiredness and fatigue
• Contributes to normal functioning of the nervous system
• Contributes to normal psychological function

Authorised EU health claims for vitamins B6, B9 and B12.

Why Methylated Forms Matter

Standard supplements use folic acid, cyanocobalamin and pyridoxine — forms that require conversion before your body can use them. NeuroThrive™ uses 5-MTHF, methylcobalamin and P-5-P — the already-active forms. For people with MTHFR variants, that's the difference between a supplement that works and one that doesn't.

Read our full guide: Methylated vs Standard B Vitamins →

Who It's For

• People with MTHFR gene variants (C677T or A1298C)
• Anyone monitoring their homocysteine levels
• Those with persistent fatigue, brain fog or low mood without a clear cause
• Anyone who hasn't felt a difference from standard B-vitamin supplements

Not sure if MTHFR affects you? Read our complete guide →

Common Questions

How is this different from a standard B-complex?
Standard B-complexes use folic acid, cyanocobalamin and pyridoxine — forms that need conversion first. NeuroThrive™ uses the already-active forms, which for people with MTHFR variants is a fundamental difference in whether the supplement does anything at all.

Can I take this if I don't know my MTHFR status?
Yes. Methylated B vitamins are suitable for the general population. Because a large share of people carry some form of the variant, many benefit before they ever get tested.

Can I take this alongside medication?
Please consult your GP or pharmacist if you take prescription medication, particularly methotrexate or anticonvulsants.

What if it doesn't suit me?
30-day money-back guarantee. Contact james@neurothrive.ie within 30 days for a full refund — no questions asked.

Why We Built It

NeuroThrive™ was founded by James O'Neill after his daughter's severe, undiagnosed MTHFR deficiency was finally identified through a blood test, following years of being told her results were normal. Her story is why this brand exists — built so others don't wait as long as his family did for answers.

Read the full story →

✅ Vegan · ✅ Non-GMO · ✅ Gluten Free · ✅ GMP Certified · ✅ FSAI Registered · ✅ Made in EU · ✅ Irish-Owned

NeuroThrive™ products are food supplements and are not intended to diagnose, treat, or cure any medical condition. Individual results may vary. Consult your GP before beginning any new supplement programme, particularly if you are pregnant, breastfeeding, or taking prescription medication.